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complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:MAPT))

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Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers v1.0.0

This document contains the bel code for the Article Alzheimer’s disease-type neuronal tau hyperphosphorylation induced by Abeta oligomers by De Felice et al

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bp(GO:"signal transduction") increases complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:MAPT)) View Subject | View Object

Inhibition occurred even though ADDLs were still bound to cell surfaces, indicating that those kinases are involved in signal transduction coupling between ADDL binding and tau hyperphosphorylation. PubMed:17403556

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complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:MAPT)) hasComponent a(HBP:"amyloid-beta derived diffusible ligands") View Subject | View Object

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complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:MAPT)) hasComponent p(HGNC:MAPT) View Subject | View Object

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complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:MAPT)) increases p(HGNC:MAPT, pmod(HBP:hyperphosphorylation)) View Subject | View Object

Inhibition occurred even though ADDLs were still bound to cell surfaces, indicating that those kinases are involved in signal transduction coupling between ADDL binding and tau hyperphosphorylation. PubMed:17403556

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.