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Entity

Name
neuroinflammation
Namespace
HBP
Namespace Version
20181119
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/90e1cb9e5e882703380c9db8d4915ac6f3cba137/export/hbp-names.belns

Appears in Networks 1

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

In-Edges 3

a(HBP:"Tau oligomers") positiveCorrelation a(HBP:neuroinflammation) View Subject | View Object

Tau Oligomers co-localize with astrocytes, microglia, and HMGB1, a pro-inflammatory cytokine, are present in the retina and are associated with inflammatory cells. PubMed:27716675

Appears in Networks:

g(DBSNP:rs63751438) positiveCorrelation a(HBP:neuroinflammation) View Subject | View Object

The tauopathy mice that we used contained the P301L mutation, which is implicated in some genetic tauopathies. In addition, this mutation, along with the related P301S mutation, has been associated with increased inflammation in the brain as well as retinal deficits PubMed:27716675

Appears in Networks:

p(HGNC:MAPT, var("p.Pro301Leu")) positiveCorrelation a(HBP:neuroinflammation) View Subject | View Object

The tauopathy mice that we used contained the P301L mutation, which is implicated in some genetic tauopathies. In addition, this mutation, along with the related P301S mutation, has been associated with increased inflammation in the brain as well as retinal deficits PubMed:27716675

Appears in Networks:

Out-Edges 3

a(HBP:neuroinflammation) positiveCorrelation p(HGNC:MAPT, var("p.Pro301Leu")) View Subject | View Object

The tauopathy mice that we used contained the P301L mutation, which is implicated in some genetic tauopathies. In addition, this mutation, along with the related P301S mutation, has been associated with increased inflammation in the brain as well as retinal deficits PubMed:27716675

Appears in Networks:

a(HBP:neuroinflammation) positiveCorrelation g(DBSNP:rs63751438) View Subject | View Object

The tauopathy mice that we used contained the P301L mutation, which is implicated in some genetic tauopathies. In addition, this mutation, along with the related P301S mutation, has been associated with increased inflammation in the brain as well as retinal deficits PubMed:27716675

Appears in Networks:

a(HBP:neuroinflammation) positiveCorrelation a(HBP:"Tau oligomers") View Subject | View Object

Tau Oligomers co-localize with astrocytes, microglia, and HMGB1, a pro-inflammatory cytokine, are present in the retina and are associated with inflammatory cells. PubMed:27716675

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.