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complex(p(HGNC:CHRM1), p(HGNC:GNA11))

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Components

Appears in Networks 1

M1 muscarinic acetylcholine receptor in Alzheimer’s disease v1.0.0

This file encodes the article M1 muscarinic acetylcholine receptor in Alzheimer’s disease by Jiang et al, 2014

In-Edges 0

Out-Edges 4

complex(p(HGNC:CHRM1), p(HGNC:GNA11)) hasComponent p(HGNC:CHRM1) View Subject | View Object

Appears in Networks:

complex(p(HGNC:CHRM1), p(HGNC:GNA11)) hasComponent p(HGNC:GNA11) View Subject | View Object

Appears in Networks:

complex(p(HGNC:CHRM1), p(HGNC:GNA11)) increases act(p(FPLX:PLC)) View Subject | View Object

So far, five mAChR subtypes (M1– M5) have been identified and are divided into two categories based on the manner of signal transduction: M1, M3, and M5 subtypes preferentially interact with the Gq/11 family of G proteins, activating phospholipase C and mobilizing intracellular calcium, while M2 and M4 subtypes couple to the Go/i family, inhibiting adenylate cyclases and reducing intracellular cAMP levels PubMed:24590577

Appears in Networks:

complex(p(HGNC:CHRM1), p(HGNC:GNA11)) increases bp(GO:"calcium ion transport") View Subject | View Object

So far, five mAChR subtypes (M1– M5) have been identified and are divided into two categories based on the manner of signal transduction: M1, M3, and M5 subtypes preferentially interact with the Gq/11 family of G proteins, activating phospholipase C and mobilizing intracellular calcium, while M2 and M4 subtypes couple to the Go/i family, inhibiting adenylate cyclases and reducing intracellular cAMP levels PubMed:24590577

Appears in Networks:

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.