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complex(p(HGNC:ATXN3, frag("?")), p(HGNC:PRKN))

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Components

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The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

In-Edges 1

p(FPLX:HSPA) increases complex(p(HGNC:ATXN3, frag("?")), p(HGNC:PRKN)) View Subject | View Object

The affinity of the polyglutamine fragment to Parkin was increased by Hsp70, in agreement with the hypothesis that molecular chaperones may play a role in the recruitment of misfolded proteins to the conjugation machinery (see, for example, Bercovich et al., 1997). PubMed:14556719

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Out-Edges 2

complex(p(HGNC:ATXN3, frag("?")), p(HGNC:PRKN)) hasComponent p(HGNC:ATXN3, frag("?")) View Subject | View Object

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complex(p(HGNC:ATXN3, frag("?")), p(HGNC:PRKN)) hasComponent p(HGNC:PRKN) View Subject | View Object

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.