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a(HBP:HBP00095)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
HBP00095
Namespace
HBP
Namespace Version
20181029
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/785431732a26d6809b4162d98b95687d16404e63/export/hbp.belns

Appears in Networks 1

Structural and functional properties of prefibrillar α-synuclein oligomers v1.0.0

In-Edges 0

Out-Edges 3

a(HBP:HBP00095) increases bp(GO:"neuron death") View Subject | View Object

Prefibrillar oligomeric α -syn has been proposed to contribute to neurodegeneration by perturbing cellular ion homeostasis20, by seeding the assembly of soluble α -syn into higher molecular weight aggregates21, and/or by imbalancing cellular proteostasis22,23. PubMed:27075649

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Lewy Bodies

a(HBP:HBP00095) decreases bp(GO:"ion homeostasis") View Subject | View Object

Prefibrillar oligomeric α -syn has been proposed to contribute to neurodegeneration by perturbing cellular ion homeostasis20, by seeding the assembly of soluble α -syn into higher molecular weight aggregates21, and/or by imbalancing cellular proteostasis22,23. PubMed:27075649

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Lewy Bodies

a(HBP:HBP00095) increases a(HBP:HBP00016) View Subject | View Object

Prefibrillar oligomeric α -syn has been proposed to contribute to neurodegeneration by perturbing cellular ion homeostasis20, by seeding the assembly of soluble α -syn into higher molecular weight aggregates21, and/or by imbalancing cellular proteostasis22,23. PubMed:27075649

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Lewy Bodies

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.