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p(HGNC:PPP1R8)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
PPP1R8
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 2

Caenorhabditis elegans models of tauopathy v1.0.0

Tau in physiology and pathology v1.0.0

In-Edges 1

p(HGNC:MAPT) increases act(p(HGNC:PPP1R8)) View Subject | View Object

Fourth, tau can regulate the release of cargo vesicles from kinesin chains by activating PP1 and glycogen synthase kinase 3β (GSK3β) via the 18 residues at the N terminus of tau PubMed:26631930

Appears in Networks:

Out-Edges 2

p(HGNC:PPP1R8) directlyDecreases p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

Protein phosphatase 1 (PP1), PP2A, PP2B, PP2C and PP5 have all been implicated in the dephosphorylation of tau PubMed:26631930

Appears in Networks:

p(HGNC:PPP1R8) directlyDecreases p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

Dephosphorylation of tau is achieved mainly by protein phosphatase (PP)2A, PP2B (calcineurin), and PP-1 (92). PubMed:29191965

Appears in Networks:

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.