Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Appears in Networks 1

APP processing in Alzheimer's disease v1.0.1

APP processing in Alzheimer's disease

In-Edges 4

a(CHEBI:"amyloid-beta") association complex(p(HGNC:APBA3), p(HGNC:APP)) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

sec(a(CHEBI:"amyloid-beta")) association complex(p(HGNC:APBA3), p(HGNC:APP)) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

a(HBP:HBP00067) association complex(p(HGNC:APBA3), p(HGNC:APP)) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

sec(a(HBP:HBP00067)) association complex(p(HGNC:APBA3), p(HGNC:APP)) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

Out-Edges 7

complex(p(HGNC:APBA3), p(HGNC:APP)) regulates bp(GO:"protein transport") View Subject | View Object

For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165] PubMed:21214928

complex(p(HGNC:APBA3), p(HGNC:APP)) association a(HBP:HBP00067) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

complex(p(HGNC:APBA3), p(HGNC:APP)) association sec(a(HBP:HBP00067)) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

complex(p(HGNC:APBA3), p(HGNC:APP)) association a(CHEBI:"amyloid-beta") View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

complex(p(HGNC:APBA3), p(HGNC:APP)) association sec(a(CHEBI:"amyloid-beta")) View Subject | View Object

APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPPalpha and Abeta generation and secretion [166] PubMed:21214928

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.