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p(MGI:Glb1)

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Entity

Name
Glb1
Namespace
MGI
Namespace Version
20170725
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mgi-mouse-genes/mgi-mouse-genes-20170725.belns

Appears in Networks 1

Tau protein aggregation is associated with cellular senescence in the brain v1.0.0

In-Edges 2

a(HP:brain) positiveCorrelation p(MGI:Glb1) View Subject | View Object

Further, SA beta-gal reactive cells were observed even in very young mice (1-month-old) and the number of SA beta-gal reactive cells was positively correlated with brain mass (R2: 0.4852, P = 0.0039 Figure S3) PubMed:30126037

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
MeSH
Alzheimer Disease

p(MGI:Mapt, var("p.Pro301Leu")) increases p(MGI:Glb1) View Subject | View Object

Examination of the gene that codes for the hydrolase enzyme, galactosidase beta 1 (Glb1), revealed that tauNFT mice expressed higher Glb1 gene expression than controls (Figure S3) PubMed:30126037

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
MeSH
Alzheimer Disease

Out-Edges 1

p(MGI:Glb1) positiveCorrelation a(HP:brain) View Subject | View Object

Further, SA beta-gal reactive cells were observed even in very young mice (1-month-old) and the number of SA beta-gal reactive cells was positively correlated with brain mass (R2: 0.4852, P = 0.0039 Figure S3) PubMed:30126037

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.