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composite(a(CHEBI:cystamine), p(HGNC:ATN1))

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The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

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Out-Edges 4

composite(a(CHEBI:cystamine), p(HGNC:ATN1)) hasComponent a(CHEBI:cystamine) View Subject | View Object

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composite(a(CHEBI:cystamine), p(HGNC:ATN1)) hasComponent p(HGNC:ATN1) View Subject | View Object

Appears in Networks:

composite(a(CHEBI:cystamine), p(HGNC:ATN1)) decreases a(HBP:"protein aggregates") View Subject | View Object

Administration of cystamine, a transglutaminase inhibitor, can reduce aggregate formation and death in cells expressing atrophin-1 (DRPLA model) (Igarashi et al., 1998) and in cells expressing mutant androgen receptor (SBMA model) (Mandrusiak et al., 2003). PubMed:14556719

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composite(a(CHEBI:cystamine), p(HGNC:ATN1)) decreases bp(GO:"cell death") View Subject | View Object

Administration of cystamine, a transglutaminase inhibitor, can reduce aggregate formation and death in cells expressing atrophin-1 (DRPLA model) (Igarashi et al., 1998) and in cells expressing mutant androgen receptor (SBMA model) (Mandrusiak et al., 2003). PubMed:14556719

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.