1. Catalog
  2. Nodes
  3. complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome))

complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease v1.0.0

In-Edges 1

path(MESH:"Alzheimer Disease") increases complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome)) View Subject | View Object

Additionally, tau appears to be physically associated with the proteasome in brain tissue from AD cases. When tau was immunoprecipitated it pulled down both the 26S and 20S proteasomes, while immunoprecipitating for the 20S catalytic core pulled down tau (69). PubMed:24027553

Appears in Networks:
Annotations
Text Location
Review

Out-Edges 2

complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome)) hasComponent p(HGNC:MAPT) View Subject | View Object

Appears in Networks:

complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome)) hasComponent p(HGNCGENEFAMILY:Proteasome) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.