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Electron Transport Complex I
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Appears in Networks 1

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage from Shafiei et al., 2017

In-Edges 2

a(HBP:"Tau oligomers") decreases a(MESH:"Electron Transport Complex I") View Subject | View Object

Also, data shows low levels of complex I in brain hemispheres injected with tau oligomers when compared to brains injected with monomers or fibrils PubMed:28420982

a(HBP:"Tau oligomers") decreases act(a(MESH:"Electron Transport Complex I")) View Subject | View Object

These results imply that tau oligomers initially affect complex I activity and may directly or indirectly disturb the later stage of complex V ATP synthesis (Lasagna-Reeves et al., 2011) PubMed:28420982

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