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Entity

Name
alpha-3 beta-4 nAChR
Namespace
HBP
Namespace Version
20181221
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/bd0996a28201cad363557315043c6392e31abf58/export/hbp-names.belns

Appears in Networks 1

albuquerque2009 v1.0.0

This file encodes the article Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function by Albuquerque et al, 2009

In-Edges 1

a(CHEBI:nicotine) increases a(HBP:"alpha-3 beta-4 nAChR") View Subject | View Object

For instance, prolonged exposure of HEK293 cells to saturating nicotine concentrations increased by 6- and 1.5-fold, respectively, the expression of alpha3beta2 and alpha3beta4 nAChRs.Similarly, while alpha4beta2 nAChRs upregulate strongly, alpha4beta4 nAChRs upregulate poorly in response to continuous exposure to nicotine. PubMed:19126755

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
HEK293
Text Location
Review

Out-Edges 0

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.