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p(HGNC:UCHL1, pmod(GO:"protein oxidation"))

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Entity

Name
UCHL1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 2

a(GO:"neurofibrillary tangle") negativeCorrelation p(HGNC:UCHL1, pmod(GO:"protein oxidation")) View Subject | View Object

A proteomic analysis has shown down-regulation and oxidative modification of UCH-L1 in the AD brain, and the levels of soluble UCH-L1 were inversely proportional to the number of NFTs (Choi et al. 2004). PubMed:22908190

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

p(HGNC:UCHL1) hasVariant p(HGNC:UCHL1, pmod(GO:"protein oxidation")) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(HGNC:UCHL1, pmod(GO:"protein oxidation")) negativeCorrelation a(GO:"neurofibrillary tangle") View Subject | View Object

A proteomic analysis has shown down-regulation and oxidative modification of UCH-L1 in the AD brain, and the levels of soluble UCH-L1 were inversely proportional to the number of NFTs (Choi et al. 2004). PubMed:22908190

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.