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a(MESH:Dyneins)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Dyneins
Namespace
mesh
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh-names.belns

Appears in Networks 3

Tau oligomers and tau toxicity in neurodegenerative disease v1.0.0

Tau oligomers and tau toxicity in neurodegenerative disease by Ward et al., 2012

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection v1.0.0

Tau in physiology and pathology v1.0.0

In-Edges 2

complex(a(GO:microtubule), a(MESH:Dyneins)) hasComponent a(MESH:Dyneins) View Subject | View Object

Appears in Networks:

p(HGNC:MAPT) association act(a(MESH:Dyneins)) View Subject | View Object

It can do this by influencing the function of the motor proteins dynein and kinesin, which transport cargoes towards the minus ends (towards the cell body) and plus ends of microtubules (towards the axonal terminus), respectively (FIG. 3). PubMed:26631930

Appears in Networks:

Out-Edges 2

a(MESH:Dyneins) increases bp(GO:"autophagosome-lysosome fusion") View Subject | View Object

Microtubule-based vesicular trafficking is essential for delivery of autophagosomes to lysosomes and subsequent fusion [46], and impaired dynein-mediated trafficking is associated with impaired autophagosome/ lysosome fusion and reduced protein turnover [47,48]. PubMed:18930136

Appears in Networks:

act(a(MESH:Dyneins)) association p(HGNC:MAPT) View Subject | View Object

It can do this by influencing the function of the motor proteins dynein and kinesin, which transport cargoes towards the minus ends (towards the cell body) and plus ends of microtubules (towards the axonal terminus), respectively (FIG. 3). PubMed:26631930

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.