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p(RGD:Stat3, pmod(Ph))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Stat3
Namespace
rgd
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/rgd-names.belns

Appears in Networks 1

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. v1.0.0

In-Edges 2

act(a(CHEBI:nicotine)) increases p(RGD:Stat3, pmod(Ph)) View Subject | View Object

Shortterm nicotine application also induces phosphorylation of p44/42MAPK, p38MAPK, and STAT-3 and was mediated mostly by alpha7 nAChRs in rat vascular smooth muscle cells (Wada et al., 2007). It is noteworthy that the JAK-2/STAT-3 pathway also mediates the mitogenic effects of insulin, a process recently implicated in AD (Li and Ho¨lscher, 2007). PubMed:19293145

Appears in Networks:
Annotations
Cell Ontology (CL)
vascular associated smooth muscle cell

p(RGD:Stat3) hasVariant p(RGD:Stat3, pmod(Ph)) View Subject | View Object

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.