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  3. p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172))

p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
2.7.11.31
Namespace
ec-code
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/ec-code.belns

Appears in Networks 1

Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β. v1.0.0

In-Edges 4

p(ECCODE:"2.7.11.31") hasVariant p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172)) View Subject | View Object

Appears in Networks:

p(ECCODE:"2.7.11.31") decreases p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172)) View Subject | View Object

AK1 overexpression markedly decreased AMPK phosphorylation at Thr172 in the primary neurons, whereas AK1 R132A mutant failed to do so PubMed:22419736

Appears in Networks:

p(HBP:"AK1 R132A") causesNoChange p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172)) View Subject | View Object

AK1 overexpression markedly decreased AMPK phosphorylation at Thr172 in the primary neurons, whereas AK1 R132A mutant failed to do so PubMed:22419736

Appears in Networks:

path(MESH:"Alzheimer Disease") decreases p(ECCODE:"2.7.11.31", pmod(Ph, Thr, 172)) View Subject | View Object

Moreover, the phosphorylation of AMPK at Thr172 tended to be reduced in AD patients, although statis- tical significance was marginal PubMed:22419736

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.