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Appears in Networks 3

In-Edges 4

a(HBP:"Tau aggregates") causesNoChange a(GO:membrane) View Subject | View Object

In our hands, these aggregated tau species formed in different conditions did not show any significant release of LDH when applied on the differentiated SH-SY5Y cells (Supplementary Fig. 8A), and they did not show a significant reduction in cell viability by the MTTassay (Supplementary Fig. 8B). PubMed:28528849

p(HBP:"Tau oligomers", var("p.Lys280del")) causesNoChange a(GO:membrane) View Subject | View Object

There was no significant change in the LDH release in oligomer-treated cells compared with controls indicating that TauRDΔK oligomers do not compromise the membrane integrity (Supplementary Fig. 5G-H). PubMed:28528849

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.