Table of Contents

Unstable Pairs 4

Chaotic Pairs
Nodes that mutually increase each other, such as when both A increases B and B increases A.
Dampened Pairs
Nodes that mutually decrease each other, such as when both A decreases B and B decreases A.

While neither chaotic nor dampened pairs are biologically invalid, they require additional context to understand their regulation.

Type Node A Node B
Chaotic bp(GO:"microglial cell activation") p(HGNC:IL1B)
Chaotic bp(GO:"astrocyte activation") p(HGNC:IL1B)
Chaotic bp(GO:"microglial cell activation") p(HGNC:IL18)
Chaotic bp(GO:"astrocyte activation") p(HGNC:IL18)

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.