The node-based overlap between this network and other networks is calculated as the Szymkiewicz-Simpson coefficient of their respective nodes. Up to the top 10 are shown below.
|BEL Framework Large Corpus Document v20170611||82%|
|BEL Framework Small Corpus Document v20150611||55%|
|Colorectal Cancer Model v2.0.6||45%|
|Growth Factor-2.0-Hs v2.0||36%|
|Endothelial Innate Immune Activation-2.0-Mm v2.0||32%|
|Growth Factor-2.0-Mm v2.0||32%|
|Selventa Protein Families Definitions v20150611||27%|
|Cell Cycle-2.0-Hs v2.0||27%|
|Neutrophil Signaling-2.0-Mm v2.0||27%|
Finally, the higher growth rate of the K12V tumors associates with enhanced Rb phosphorylation, and PCNA and cyclin B upregulation, consistent with faster G1/S and G2/M transitions, without alteration of apoptotic regulation.
BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of the open source project, PyBEL. Please feel free to contact us here to give us feedback or report any issues.