p(MGI:Dcaf1) association p(MGI:Dyrk1a)

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PubMed:28137862

Moreover, we found that Hap1 bound Dcaf7 competitively in cytoplasm with dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), a protein implicated in Down syndrome (DS). Depleting Hap1 promoted the DYRK1A-Dcaf7 interaction and increased the DYRK1A protein level.

Related Edges 7

• complex(p(MGI:Dcaf1), p(MGI:Dyrk1a)) negativeCorrelation p(MGI:Hap1)
• p(MGI:Dcaf1) association p(MGI:Hap1)
• p(MGI:Dyrk1a) association p(MGI:Dcaf1)
• p(MGI:Dyrk1a) negativeCorrelation p(MGI:Hap1)
• p(MGI:Hap1) association p(MGI:Dcaf1)
• p(MGI:Hap1) negativeCorrelation p(MGI:Dyrk1a)
• p(MGI:Hap1) negativeCorrelation complex(p(MGI:Dcaf1), p(MGI:Dyrk1a))

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