act(p(ECCODE:"2.3.2.13")) positiveCorrelation a(GO:"neurofibrillary tangle")

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PubMed:8985134

Degenerating neurons from the AD hippocampus, compared to neurons from the normal aged hippocampus, exhibited increased immunoreactivity for TGase and demonstrated co-labeling for PHF1 and anti-TGase. Our results suggest that TGase may be associated with the neurofibrillary degeneration observed in AD, thereby implicating TGase as a potential factor in the pathogenesis of Alzheimer's disease.

Related Edges 3

• a(GO:"neurofibrillary tangle") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
• act(p(ECCODE:"2.3.2.13")) positiveCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:"2.3.2.13"))

Uberon

hippocampal formation

Disease Ontology (DO)

Alzheimer's disease

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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