path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:"2.3.2.13"))

View Subject View Object

PubMed:8985134

Degenerating neurons from the AD hippocampus, compared to neurons from the normal aged hippocampus, exhibited increased immunoreactivity for TGase and demonstrated co-labeling for PHF1 and anti-TGase. Our results suggest that TGase may be associated with the neurofibrillary degeneration observed in AD, thereby implicating TGase as a potential factor in the pathogenesis of Alzheimer's disease.

Related Edges 3

• a(GO:"neurofibrillary tangle") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
• act(p(ECCODE:"2.3.2.13")) positiveCorrelation a(GO:"neurofibrillary tangle")
• act(p(ECCODE:"2.3.2.13")) positiveCorrelation path(MESH:"Alzheimer Disease")

Uberon

hippocampal formation

Disease Ontology (DO)

Alzheimer's disease

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---