sec(a(MESH:Hydrolases)) increases path(MESH:Necrosis)

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PubMed:22908190

Cataclysmic disruption of lysosomal membranes releases hydrolases that act as both the trigger and executioner in rapid necrosis (Syntichaki et al. 2003; Kroemer et al. 2005), whereas slow release of cathepsins more likely operates through signaling pathways to trigger apoptosis (Kroemer et al. 2005).

Related Edges 1

• sec(a(MESH:Cathepsins)) increases bp(GO:"apoptotic process")

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