p(SFAM:"HSP90 Family") increases complex(p(HGNC:MAPT), p(SFAM:"HSP90 Family"))

View Subject View Object

PubMed:19363271

This result suggests that the VQIVYK peptide plays a role in the interaction between Hsp90 and tau protein, a hypothesis which is also supported by the fact that a tau variant deleted for the peptide VQIVYK was unable to interact with Hsp90 under immunoprecipitation conditions (Fig. 2B).

Related Edges 3

• p(HBP:"VQIVYK motif") increases complex(p(HGNC:MAPT), p(SFAM:"HSP90 Family"))
• p(SFAM:"HSP90 Family") association p(HBP:"VQIVYK motif")
• p(HBP:"VQIVYK motif") association p(SFAM:"HSP90 Family")

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---