act(p(HGNC:SYK)) positiveCorrelation a(HBP:"amyloid-beta aggregates")

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PubMed:28877763

We found an increase in Syk activation in DNs surrounding A β deposits as well as in neurons displaying an accumu- lation of phosphorylated Tau at Y18 and elevated levels of MC1 pathogenic tau conformers in AD brain sections whereas only weak immunoreactivity for pSyk was ob- served in brain sections from a non-demented control (Figs. 15, 16 and 17).

Related Edges 5

• a(HBP:"amyloid-beta aggregates") positiveCorrelation act(p(HGNC:SYK))
• p(HGNC:MAPT, pmod(HBP:misfolded)) positiveCorrelation act(p(HGNC:SYK))
• p(HGNC:MAPT, pmod(Ph, Tyr, 18)) positiveCorrelation act(p(HGNC:SYK))
• act(p(HGNC:SYK)) positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 18))
• act(p(HGNC:SYK)) positiveCorrelation p(HGNC:MAPT, pmod(HBP:misfolded))

MeSH

Neurites

MeSH

Brain

MeSH

Alzheimer Disease

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