p(HGNC:MAPT, pmod(HBP:"O-GlcNAcylation")) negativeCorrelation p(HGNC:MAPT, pmod(Ph))

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PubMed:16630055

We recently discovered that the human brain tau is also modified by O-GlcNAcylation in addition to phosphorylation and that O-GlcNAcylation modulates phosphorylation of tau inversely (Liu et al.,2004a). We found that fasting induced a time-dependent decrease in tau O-GlcNAcylation and concurrent hyperphosphorylation of tau at most of the phosphorylation sites studied.

Related Edges 5

• a(CHEBI:glucose) negativeCorrelation path(MESH:Fasting)
• p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:MAPT, pmod(HBP:"O-GlcNAcylation"))
• path(MESH:Fasting) decreases p(MGI:Mapt, pmod(HBP:"O-GlcNAcylation"))
• path(MESH:Fasting) increases p(MGI:Mapt, pmod(Ph))
• path(MESH:Fasting) negativeCorrelation a(CHEBI:glucose)

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