a(CHEBI:"reactive oxygen species") association bp(MESH:"Membrane Fluidity")

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PubMed:27288790

Higher levels of ROS biomarkers are characteristic of AD patients in clinical and preclinical studies, resulting in the alteration of membrane proper- ties, such as fluidity, ion transport, enzyme activities, protein cross- linking, tau protein hyperphosphorylation, autophagic dysfunction and eventually neuron cell death [20].

Related Edges 7

• a(CHEBI:"reactive oxygen species") positiveCorrelation path(MESH:"Alzheimer Disease")
• a(CHEBI:"reactive oxygen species") association bp(GO:"ion transport")
• a(CHEBI:"reactive oxygen species") increases p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
• a(CHEBI:"reactive oxygen species") decreases bp(GO:autophagy)
• bp(GO:"ion transport") association a(CHEBI:"reactive oxygen species")
• bp(MESH:"Membrane Fluidity") association a(CHEBI:"reactive oxygen species")
• path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"reactive oxygen species")

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