complex(FPLX:"Gamma_secretase") increases p(HGNC:APP, frag("672_711"))

View Subject View Object

PubMed:22122372

gamma-Secretase cleaves APP at multiple sites and in sequential steps to generate Abeta peptides of different lengths (Fig. 1). The majority of Abeta peptides produced are 40 amino acids long, however, peptides ranging from 38 to 43 amino acids are found in vivo

Related Edges 2

• complex(FPLX:"Gamma_secretase") increases p(HGNC:APP, frag("1_38"))
• complex(FPLX:"Gamma_secretase") increases p(HGNC:APP, frag("1_43"))

Confidence

Medium

MeSH

Neurons

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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