a(PUBCHEM:675434) decreases p(HGNC:ATXN3)

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PubMed:25784053

Treatment with IU1 reduced the levels of Tau, TDP-43, and ataxin-3 in MEFs in a USP14-dependent manner and independently of changes in proteasome levels or composition (147).

Related Edges 4

• a(PUBCHEM:675434) decreases p(HGNC:MAPT)
• a(PUBCHEM:675434) decreases p(HGNC:TARDBP)
• a(PUBCHEM:675434) decreases act(p(HGNC:USP14))
• a(PUBCHEM:675434) causesNoChange p(FPLX:Proteasome)

Experimental Factor Ontology (EFO)

MEF cell line

Cell Ontology (CL)

motor neuron

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