a(PUBCHEM:64627) increases a(GO:"dendritic spine")

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PubMed:27671637

Indeed, the reduced level of spines seen in proaggregant Tau transgenic slices are normalized when treated with 64627, whereas no significant changes are found in antiaggregant Tau transgenic slices or littermate controls (Fig. 5 A and B)

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• composite(a(PUBCHEM:64627), p(HBP:"Tau isoform F (441 aa)", var("p.Ile277Pro"), var("p.Ile308Pro"), var("p.Lys280del"))) causesNoChange a(GO:"dendritic spine")
• composite(a(PUBCHEM:64627), p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))) increases a(GO:"dendritic spine")

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