p(HGNC:ADAM10) increases sec(p(HGNC:APP))

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PubMed:22122372

APP can also be cleaved by alpha-secretase to form a soluble or secreted APP ectodomain (sAPP-alpha) that has been shown to be mostly neuro-protective

Related Edges 2

• a(HBP:HBP00067) decreases bp(HBP:HBP00061)
• p(HGNC:ADAM10) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:HBP00067)))

Confidence

High

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