a(CHEBI:heme) increases bp(GO:"complement activation, alternative pathway")

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PubMed:26875449

Heme exposure of other proteins in the alternative pathway (factors B, D, and H) does not appear to have any impact on their functions, thus implying that heme activates the alternative complement pathway by affecting C3 directly [33].

Related Edges 3

• a(CHEBI:heme) causesNoChange p(HGNC:CFB)
• a(CHEBI:heme) causesNoChange p(HGNC:CFD)
• a(CHEBI:heme) causesNoChange p(HGNC:CFH)

Cell Ontology (CL)

erythrocyte

MeSH

Malaria

Text Location

Review

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