p(HGNC:FYN) increases p(HGNC:MAPT, pmod(Ph))

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PubMed:18680553

Furthermore, Tau binds Fyn both in neuronal and oligodendroglial cells (Brandt et al. 1995; Klein et al.2002), and Fyn phosphorylates Tau in neuronal cells (Lee et al. 2004). The main Fyn SH3 domain-binding PXXP motif (Pro, Lys, Ser, Pro) in adult rat Tau is at the residues 223-226 (Kosik et al. 1989; Lee et al. 1998).

Related Edges 4

• p(HGNC:MAPT) association p(HGNC:FYN)
• p(HGNC:FYN) association p(HGNC:MAPT, frag("223_226"))
• p(HGNC:FYN) association p(HGNC:MAPT)
• p(HGNC:MAPT, frag("223_226")) association p(HGNC:FYN)

Cell Ontology (CL)

neuron

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