a(CHEBI:"zinc(2+)") increases act(p(MESH:"Receptors, Nicotinic"))

View Subject View Object

PubMed:23038257

One group of modulators includes Ca2+􏰆, which potentiates most neuronal nAChRs (99, 100) and binds to the extracellular domain below the ACh site at residues contributed from both sides of the subunit interface (96). Another includes Zn2 􏰆 .

Related Edges 1

• a(CHEBI:"calcium(2+)") increases act(p(MESH:"Receptors, Nicotinic"))

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---