act(a(CHEBI:"Hsp90 inhibitor")) decreases p(HGNC:MAPT)

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PubMed:24027553

For example, treatment of primary neurons with an Hsp90 inhibitor to interrupt the proper chaperoning of tau leads to decreased levels of tau. Adding MG-132 to block the proteasome prevented the Hsp90 inhibitor-induced reduction in total tau. MG-132 alone had no effect on tau levels (67).

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• a(CHEBI:"N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal") decreases act(a(CHEBI:"Hsp90 inhibitor"))

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