a(HBP:HBP00093) increases bp(GO:"apoptotic process")

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PubMed:27075649

α -syn fibrils revealed to be highly toxic to cells at all the concentrations we tested, spanning 1 to 0.01 nM (53.4 ± 4% inhibition of MTT reduction at 0.01 nM, i.e. 0.1 μM equivalent monomer concentration) whereas α -syn oligomers only slightly impaired cell viability (23.9 ± 6% inhibition of MTT reduction at 300 nM, i.e. 10 μM initial monomer concentration) (Fig. 3c).

Related Edges 1

• a(HBP:HBP00092) increases bp(GO:"apoptotic process")

MeSH

Intracellular Space

Cell Ontology (CL)

neuron

Confidence

High

MeSH

Lewy Bodies

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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