composite(a(CHEBI:Nilvadipine), p(HGNC:TNF)) decreases act(complex(GO:"NF-kappaB complex"))

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PubMed:25331948

Weobserved that (-)-nilvadipine inhibits NFkB activation in response to TNFα (Fig. 4A) or phorbol 12-myristate 13-acetate (PMA) (Fig. 4B) by using an NFkB-luciferase reporter cell line to monitor NFkB activation, thus suggesting a possible mechanism responsible for the inhibition of BACE-1 transcription following nilvadipine treatment

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• composite(a(CHEBI:"phorbol 13-acetate 12-myristate"), a(CHEBI:Nilvadipine)) decreases act(complex(GO:"NF-kappaB complex"))

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