a(CHEBI:calcitriol) decreases p(HGNC:AGER)

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PubMed:29626319

1,25(OH)2D3, the active form of vitamin D, plays a key role in enhancing transport of Aβ1–40 from the brain to the blood by reducing RAGE levels at the BBB, and also in contributing to periphery clearance by increasing levels of LRP1 both in vivo and in vitro (Guo et al. 2016b)

Related Edges 2

• a(CHEBI:calcitriol) increases tloc(a(CHEBI:"amyloid-beta polypeptide 40"), fromLoc(MESH:Brain), toLoc(MESH:Blood))
• a(CHEBI:calcitriol) increases p(HGNC:LRP1)

MeSH

Blood-Brain Barrier

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