p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197)) positiveCorrelation path(HBP:"Corticobasal Degeneration")

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PubMed:22057784

Tau-nY18 did not label the classical pathological lesions of CBD or PSP but did label the neuronal lesions associated with PiD. Tau-nY29 revealed some, but not all classes of tau inclusions associated with both CBD and PSP but did label numerous Pick body inclusions in PiD. Tau-nY197 was restricted to the neuropil threads in both CBD and PSP; however, similar to Tau-nY29, extensive Pick body pathology was clearly labeled. Tau-nY394 did not detect any of the lesions associated with these disorders.

Related Edges 9

• p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18)) positiveCorrelation path(MESH:"Pick Disease of the Brain")
• p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197)) positiveCorrelation path(MESH:"Supranuclear Palsy, Progressive")
• p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29)) positiveCorrelation path(MESH:"Pick Disease of the Brain")
• p(HGNC:MAPT, pmod(NO, Tyr, 29)) positiveCorrelation path(MESH:"Pick Disease of the Brain")
• path(HBP:"Corticobasal Degeneration") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197))
• path(MESH:"Pick Disease of the Brain") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18))
• path(MESH:"Pick Disease of the Brain") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29))
• path(MESH:"Pick Disease of the Brain") positiveCorrelation p(HGNC:MAPT, pmod(NO, Tyr, 29))
• path(MESH:"Supranuclear Palsy, Progressive") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197))

Uberon

neuropil

Disease Ontology (DO)

progressive supranuclear palsy

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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