path(MESH:"Neurogenic Inflammation") positiveCorrelation path(MESH:"Alzheimer Disease")

PubMed:19126755

AD is the most common form of dementia in the elderly population. The histopathology of this disease is well known to have at least four components: 1) loss of cholinergic neurotransmission, 2) deposition of extracellular Abeta peptides into plaques, 3) hyperphosphorylation of the tau protein that leads to excessive formation of neurofibrillar tangles, and 4) increased local inflammation.

Related Edges 9

• bp(GO:"synaptic transmission, cholinergic") negativeCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Dementia)
• path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"synaptic transmission, cholinergic")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurogenic Inflammation")
• path(MESH:"Neurofibrillary Tangles") positiveCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:Dementia) positiveCorrelation path(MESH:"Alzheimer Disease")

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