a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Thr, 205))

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PubMed:22798221

Here, we found that MG could induce tau hyperphosphorylation at multiple AD-related sites in neuroblastoma 2a cells under maintaining normal cell viability. MG treatment increased the level of advanced glycation end products (AGEs) and the receptor of AGEs (RAGE).

Related Edges 8

• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Ser, 199))
• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Ser, 404))
• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Ser, 198))
• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Ser, 202))
• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Thr, 231))
• a(CHEBI:methylglyoxal) increases p(MGI:Mapt, pmod(Ph, Ser, 396))
• a(CHEBI:methylglyoxal) increases a(CHEBI:"advanced glycation end-product")
• a(CHEBI:methylglyoxal) increases p(HGNC:AGER)

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