p(HGNC:PPP2R5D) decreases p(HGNC:MAPT, pmod(Ph))

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PubMed:24653673

Knock-down of PP2A catalytic subunit (Kins et al.,2001) or PP2A B’δ (or PPP2R5D) regulatory subunit (Louis et al.,2011), and expression of the methylation-site L309A C subunit mutant (Schild et al.,2006) all induce AD-like tau phosphorylation in transgenic mice

Related Edges 4

• p(HGNC:PPP2CA) decreases p(HGNC:MAPT, pmod(Ph))
• p(HGNC:PPP2CB) decreases p(HGNC:MAPT, pmod(Ph))
• p(HGNC:PPP2CA, var("p.Leu309Ala")) increases p(HGNC:MAPT, pmod(Ph))
• p(HGNC:PPP2CB, var("p.Leu309Ala")) increases p(HGNC:MAPT, pmod(Ph))

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