p(HGNC:GSK3B) increases p(HBP:HBP00071, pmod(Ph, Thr, 668))

View Subject View Object

PubMed:22122372

AICD also contains three phosphorylation sites, including two threonine residues at 654 and 668 and a serine residue at 665. AICD has been found to be phosphorylated by PKC, calcium-calmodulin dependent-kinase II, GSK3-b, Cdk5 and c-Jun N-terminal kinase (JNK) at the Ser/Thr sites mentioned above

Related Edges 14

• a(MESH:"JNK Mitogen-Activated Protein Kinases") increases p(HBP:HBP00071, pmod(Ph, Thr, 654))
• a(MESH:"JNK Mitogen-Activated Protein Kinases") increases p(HBP:HBP00071, pmod(Ph, Thr, 668))
• a(MESH:"JNK Mitogen-Activated Protein Kinases") increases p(HBP:HBP00071, pmod(Ph, Ser, 665))
• p(HGNC:CAMK2A) increases p(HBP:HBP00071, pmod(Ph, Thr, 654))
• p(HGNC:CAMK2A) increases p(HBP:HBP00071, pmod(Ph, Thr, 668))
• p(HGNC:CAMK2A) increases p(HBP:HBP00071, pmod(Ph, Ser, 665))
• p(HGNC:CDK5) increases p(HBP:HBP00071, pmod(Ph, Thr, 654))
• p(HGNC:CDK5) increases p(HBP:HBP00071, pmod(Ph, Thr, 668))
• p(HGNC:CDK5) increases p(HBP:HBP00071, pmod(Ph, Ser, 665))
• p(HGNC:GSK3B) increases p(HBP:HBP00071, pmod(Ph, Thr, 654))
• p(HGNC:GSK3B) increases p(HBP:HBP00071, pmod(Ph, Ser, 665))
• p(HGNC:PRKCA) increases p(HBP:HBP00071, pmod(Ph, Thr, 654))
• p(HGNC:PRKCA) increases p(HBP:HBP00071, pmod(Ph, Thr, 668))
• p(HGNC:PRKCA) increases p(HBP:HBP00071, pmod(Ph, Ser, 665))

Confidence

High

MeSH

Neurons

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---