p(MGI:Hpx) decreases r(MGI:Gsr)

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PubMed:28400318

Consistently, the mRNA levels of Glutathione reductase (Gsr), -Glutamylcysteine synthetase (-Gcs) and thioredoxin reductase (Thiored red), anti-oxidant systems important in resistance of cardiac cell to oxidative damage [40, 41], were increased to a higher extent in CMs treated with either albumin heme or heme alone, compared to cells treated with Hx-heme (Figure 1F and see Figure 3 in [37]).

Related Edges 5

• a(CHEBI:heme) increases r(MGI:Gsr)
• a(CHEBI:heme) increases r(MGI:Gclc)
• a(CHEBI:heme) increases complex(r(MGI:Txnrd1), r(MGI:Txnrd2), r(MGI:Txnrd3))
• p(MGI:Hpx) decreases r(MGI:Gclc)
• p(MGI:Hpx) decreases complex(r(MGI:Txnrd1), r(MGI:Txnrd2), r(MGI:Txnrd3))

Cell Ontology (CL)

regular cardiac myocyte

Text Location

Results

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