a(CHEBI:heme) increases bp(GO:"complement activation, alternative pathway")

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PubMed:26875449

It is possible that heme-induced overactivation of the alternative complement pathway, and depo- sition of C3 fragments on erythrocyte membranes, participate in erythrophagocytosis of uninfected red blood cells in severe forms of malaria [77].

Related Edges 2

• a(HM:erythrophagocytosis) positiveCorrelation bp(GO:"complement activation, alternative pathway")
• bp(GO:"complement activation, alternative pathway") positiveCorrelation a(HM:erythrophagocytosis)

Cell Ontology (CL)

erythrocyte

MeSH

Malaria

Text Location

Review

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