p(HGNC:SORL1) decreases a(CHEBI:"amyloid-beta")

PubMed:18650430

Finally, the type I transmembrane protein SorLA/LR11 (a member of the VPS10p domain receptor fam- ily), which functionally interacts with cytosolic adaptors GGA and PACS-1, attenuates Aβ production by acting as a Golgi/ TGN retention factor (22).

Confidence

High

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