p(HGNC:CHRNA7) association bp(MESH:"Sensory Gating")

PubMed:19721446

in addition, a decrease in alpha7 nAChR density in the hippocampus of patients with schizophrenia has been reported177. Similarly, a low density of alpha7 nAChRs in inbred strains of mice is associated with poor gating178. Recently, the expression of a novel variant of alpha7 nAChR, CHRNA7-2 (cholinergic receptor, nicotinic, alpha7, variant 2), was found to be reduced below control levels in the prefrontal cortex of patients with schizophrenia179.

Related Edges 2

• bp(MESH:"Sensory Gating") association p(HGNC:CHRNA7)
• path(MESH:Schizophrenia) decreases p(HGNC:CHRNA7)

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