p(MGI:Hmox1) negativeCorrelation path(MESH:"Mitochondrial Diseases")

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PubMed:25301065

During heme exposure the Hmox1 (−/ −) cells show a dose-dependent decrease in mitochondrial function as indicated by decreased cellular ATP (Figure 1c) and parallel induction of caspase 3/7 activity (Figure 1d) as well as nuclear condensation (Figure 1e) that occurred at heme concentrations exceeding 10 μM.

Related Edges 3

• a(CHEBI:heme) positiveCorrelation path(MESH:"Mitochondrial Diseases")
• path(MESH:"Mitochondrial Diseases") positiveCorrelation a(CHEBI:heme)
• path(MESH:"Mitochondrial Diseases") negativeCorrelation p(MGI:Hmox1)

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