p(HGNC:PICALM) positiveCorrelation p(HGNC:BECN1)

View Subject View Object

PubMed:27260836

A highly significant correlation was found between decreased levels of PICALM and increased levels of LC3-II (p=0.0032) or decreased levels of Beclin-1 (p=0.0295) in the total brain lysates from these diseases (Fig 6D,E).

Related Edges 3

• p(HGNC:BECN1) positiveCorrelation p(HGNC:PICALM)
• p(HGNC:MAP1LC3B) negativeCorrelation p(HGNC:PICALM)
• p(HGNC:PICALM) negativeCorrelation p(HGNC:MAP1LC3B)

Disease Ontology (DO)

Alzheimer's disease

Disease Ontology (DO)

Down syndrome

Disease Ontology (DO)

Pick's disease

Disease Ontology (DO)

progressive supranuclear palsy

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---