a(MESH:Fetus) increases r(HGNC:CHRNA3, loc(MESH:Brain))

PubMed:19126755

For instance, the alpha3 nAChR transcript generally dominates in the prenatal brain or in injured neurons, whereas its expression tends to be downregulated in the adult or healthy neuron, and alpha4 transcription is increased.

Related Edges 5

• a(MESH:Adult) decreases r(HGNC:CHRNA3)
• a(MESH:Adult) increases r(HGNC:CHRNA4)
• a(MESH:Neurons) decreases r(HGNC:CHRNA3)
• a(MESH:Neurons) increases r(HGNC:CHRNA4)
• path(MESH:"Trauma, Nervous System") increases r(HGNC:CHRNA3, loc(MESH:Brain))

Text Location

Review

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.